Mean±SD from baseline and multiple follow-ups in the characteristic
| Variable | Time (months) | P value* | ||
| 0 | 6 | 12 | ||
| Weight | 120.17±17.77 | 87.83±12.42 | 81.04±11.47 | ˂0.001 |
| BMI (kg/m2) | 45.01±4.43 | 32.93±3.29 | 30.39±3.12 | ˂0.001 |
| Fat mass (kg) | 58.37±10.19 | 34.89±8.55 | 29.08±8.15 | ˂0.001 |
| FFM (kg) | 61.79±12.23 | 52.93±10.14 | 51.96±9.45 | ˂0.001 |
| TWL (%) | – | 26.77±4.85 | 32.40±5.73 | ˂0.001 |
| EWL (%) | – | 61.37±11.74 | 74.04±13.06 | ˂0.001 |
| CRI-I | 4.22±1.18 | 3.77±0.98 | 3.20±0.79 | ˂0.001 |
| CRI-II | 2.36±0.83 | 2.15±0.74 | 1.81±0.63 | ˂0.001 |
| TG to HDL-C ratio | 1.47±0.78 | 1.02±0.51 | 0.80±0.32 | ˂0.001 |
| TyG index | 8.94±0.53 | 8.51±0.39 | 8.32±0.30 | ˂0.001 |
| AIP | 0.46±0.22 | 0.32±0.17 | 0.23±0.15 | ˂0.001 |
| LCI | 21.71±17.13 | 13.72±9.26 | 9.17±6.56 | ˂0.001 |
| CHOLINDEX | 1.36±0.83 | 1.15±0.74 | 0.81±0.63 | ˂0.001 |
| AC | 3.22±1.18 | 2.77±0.98 | 2.20±0.79 | ˂0.001 |
*One-way repeated measure analysis of variance was used to compare differences of variables by the three time points.
AC, atherogenic coefficient; AIP, atherogenic index of plasma; BMI, body mass index; CHOLINDEX, cholesterol index; CRI-I, castelli risk index-I; CRI-II, castelli risk index-II; EWL, Excess weight loss; FFM, fat free mass; FM, Fat mass; HDL-C, high-density lipoprotein-cholesterol; LCI, lipoprotein combine index; TG, triglyceride; TWL, total weight loss; TyG, triglyceride glucose.