Table 1

Attrition table of study patient population in phase I

Patient size by BM methodBreast cancerNSCLCProstate cancer
N%N%N%
Eligible cohort at feasibility stage614210052021005382100
Patient cohort identified with BM in the medical records5739.389917.3101718.9
 Patients identified by NLP of reports *52792.082992.296394.7
 Patients identified as receiving BTA treatment *30953.911813.112912.7
 Patients identified as patient having SCC *193.3414.6424.1
 Patients identified in coded EMR field *498.6<75555.4
Final cohort of patients with BM after further clinical review5599.089417.0101318.8
  • *Number of patients identified as BM by each method of the overall eligible cohort and confirmed after review by two clinical physicians (patient can be identified in multiple methods).

  • BM, bone metastasis; BTA, bone-targeting agents; EMR, electronic medical record; NLP, natural language processing; NSCLC, non-small cell lung cancer; SCC, spinal cord compression.