Results from adjusted linear regression analyses, n=1539
| Model covariates | Birth weight regression coefficient (95% CI) | P value | Head circumference regression coefficient (95% CI) | P value | Length regression coefficient (95% CI) | P value |
| THC positive | −0.16 (−0.22 to −0.10) | <0.001 | −0.52 (−0.78 to −0.27) | <0.001 | −0.71 (−1.03 to −0.39) | <0.001 |
| Patient characteristics | ||||||
| Maternal age | 0.01 (0.00 to 0.01) | 0.032 | 0.02 (0.01 to 0.04) | 0.009 | 0.02 (−0.01 to 0.05) | 0.159 |
| Race/ethnicity | ||||||
| White | referent | 0.449 | referent | 0.861 | referent | 0.212 |
| Black | −0.04 (−0.21 to 0.12) | −0.01 (−0.88 to 0.85) | −0.51 (−1.65 to 0.62) | |||
| Hispanic | −0.04 (−0.15 to 0.07) | −0.09 (−0.48 to 0.30) | −0.30 (−0.99 to 0.40) | |||
| Other/unknown | 0.06 (−0.04 to 0.16) | −0.16 (−0.56 to 0.25) | 0.42 (-0.09 to 0.93) | |||
| Comorbidities and risk factors | ||||||
| Tobacco use | −0.15 (−0.21 to −0.09) | <0.001 | −0.41 (−0.64 to −0.17) | 0.001 | −0.79 (−1.12 to −0.46) | <0.001 |
| Alcohol use | −0.12 (−0.31 to 0.07) | 0.228 | −0.78 (−2.01 to 0.45) | 0.214 | −0.56 (−1.48 to 0.36) | 0.232 |
| Diabetes | 0.03 (−0.05 to 0.11) | 0.462 | −0.01 (−0.33 to 0.32) | 0.957 | 0.14 (−0.32 to 0.59) | 0.550 |
| Hypertension | −0.18 (−0.25 to −0.10) | <0.001 | −0.36 (−0.62 to −0.10) | 0.008 | −0.72 (−1.14 to −0.29) | 0.001 |
| Cervical insufficiency | −0.18 (−0.43 to 0.08) | 0.173 | −0.48 (−1.53 to 0.56) | 0.362 | −1.61 (−3.52 to 0.30) | 0.099 |
| Multiple gestation | −0.66 (−0.84 to −0.49) | <0.001 | −1.47 (−2.13 to −0.81) | <0.001 | −3.48 (−4.49 to −2.47) | <0.001 |
Multivariable linear regression controlled for tobacco use, alcohol use, diabetes, hypertension, cervical insufficiency, and multiple gestation. Note: there was one patient missing age and was excluded from multiple regression models
Bold values denote statistical significance.
THC, tetrahydrocannabinol.