Demographic and biochemical characteristics, FIB-4 and TE scores of the study participants
Variable (unit measure) | Entire group Mean (SD) | Unsplenectomised group Mean (SD) | Splenectomy group Mean (SD) | P value |
Age (years) | 18.9 (4.8) | 17.7 (4.8) | 21.1 (3.97) | 0.02 |
AST (IU/L) | 47 (27.5) | 41.8 (26.5) | 57.73 (27.3) | 0.007 |
ALT (IU/L) | 60 (46.35) | 55.7 (50.4) | 68.96 (36.8) | 0.08 |
Platelet count(cells/*103 mm3) | 329 (186) | 272 (100) | 442 (259) | 0.11 |
FIB-4 score | 0.46 (0.32) | 0.43 (0.22) | 0.53 (0.46) | 0.97 |
TE score (kPa) | 10.22 (6.42) | 7.75 (2.46) | 15.2 (8.8) | 0.002 |
FIB-4=age (years) * AST [U/L]/(platelets [109/L] * (ALT [U/L])1/2).
ALT, alanine aminotransferase; AST, aspartate aminotransferase; FIB-4, fibrosis-4; IU/L, international units per liter ; TE, transient elastography.