Age-specific and sex-specific risks of suicide, suicidal attempts/ideation during use of methylphenidate
| Characteristic | Cases/controls (n) | HR (95% CI) |
| Women | 64/44 043 | 3.9 (1.5 to 10.2) |
| Men | 65/52 294 | 1.1 (0.4 to 2.6) |
| 18–40 years of age | 84/62 196 | 2.4 (1.2 to 4.9) |
| 41–60 years of age | 38/28 108 | 1.3 (0.4 to 4.9) |
| 61–80 years of age | 4/4543 | 1.6 (0.0 to ∞) |
| >80 years of age | 3/836 | –* |
All hazard ratios (HR) are adjusted for sex, age, intervention, smoking, BMI, alcohol abuse, acute alcohol intoxication, medicines abuse, tobacco abuse, drug abuse, psychosis in history (for non-psychotic endpoints), depression in history (for non-depressive endpoints), anxiety in history (for non-anxiety endpoints), neuroses in history, personality disorder, other psychiatric disease and ‘intention-to-treat’.
*No cases exposed to methylphenidate.
BMI, body mass index.