Hierarchy of evidence
Evidence level | Study design |
I | Evidence from systematic reviews or meta-analyses of randomised controlled clinical trials (RCTs). |
II | Evidence from a well-designed RCT. |
III | Evidence from well-designed controlled clinical trials without randomization (quasiexperimental). |
IV | Evidence from well-designed case–control, cohort or cross-sectional studies. |
V | Evidence from systematic reviews of qualitative and descriptive studies. |
VI | Evidence from a single descriptive or qualitative study. |
VII | Evidence from the opinion of authorities and/or reports of expert committees. |