Summary of participant-reported outcome measures at all time points and mean differences with corresponding 95% CIs
| Measure (scale range) | T0 Mean (SD) (range) | T1 Mean (SD) (range) | T2 Mean (SD) (range) | T1-T0 Mean difference (95% CI) | T2-T0 Mean difference (95% CI) |
| BRAF-NRS fatigue effect (0–10) | 8.48 (1.19) (6.00–10.00) (n=46) | 6.68 (1.54) (4.00–9.00) (n=40) | 6.03 (2.72) (0.00–10.00) (n=39) | −1.78 (−2.27 to −1.28) (n=40) | −2.41 (−3.29 to −1.53) (n=39) |
| BRAF-NRS coping (0–10) | 6.68 (2.25) (1.00–10.00) (n=41) | 5.79 (2.53) (0.00–10.00) (n=34) | 5.03 (2.72) (0.00–10.00) (n=34) | −0.59 (−1.53 to 0.34) (n=32) | −1.06 (−2.00 to −0.12) (n=32) |
| RAID final score (0–10) | 6.40 (1.60) (1.87–9.25) (n=41) | 5.57 (2.00) (1.65–8.79) (n=34) | 5.54 (1.91) (1.30–8.79) (n=36) | −0.64 (−1.27 to −0.00) (n=32) | −0.61 (−1.32 to 0.10) (n=33) |
| BRAF-MDQ physical severity (0–22) | 17.92 (2.82) (11.00–22.00) (n=41) | 14.97 (4.16) (5.00–22.00) (n=34) | 14.56 (5.22) (4.00–22.00) (n=34) | −2.44 (−3.75 to −1.12) (n=32) | −2.87 (−4.85 to −0.89) (n=30) |
| BRAF-MDQ living with fatigue (0–21) | 12.42 (4.95) (4.00–21.00) (n=41) | 9.09 (6.10) (0.00–21.00) (n=34) | 8.63 (5.88) (0.00–21.00) (n=34) | −2.75 (−4.52 to −0.98) (n=32) | −2.72 (−4.55 to −0.88) (n=30) |
| BRAF-MDQ cognitive (0–15) | 9.39 (3.93) (1.00–15.00) (n=41) | 7.62 (3.82) (0.00–15.00) (n=34) | 7.09 (3.51) (1.00–15.00) (n=34) | −1.84 (−3.19 to −0.50) (n=32) | −1.63 (−3.22 to 0.05) (n=30) |
| BRAF-MDQ emotional (0–12) | 7.71 (3.16) (1.00–12.00) (n=41) | 5.44 (3.51) (1.00–12.00) (n=34) | 5.47 (3.52) (0.00–12.00) (n=34) | −1.47 (−2.51 to −0.42) (n=32) | −1.67 (−3.06 to −0.27) (n=30) |
| BRAF-MDQ total (0–70) | 47.43 (12.60) (21.00–66.00) (n=41) | 37.12 (15.39) (14.00–68.00) (n=34) | 35.75 (15.84) (9.00–66.00) (n=34) | −8.50 (−13.03 to −3.97) (n=32) | −8.88 (−15.00 to −2.77) (n=30) |
| MHAQ mean score (0–4) | 0.84 (0.58) (0.00–2.38) (n=41) | 0.72 (0.55) (0.00–2.13) (n=33) | 0.81 (0.61) (0.00–2.00) (n=34) | −0.07 (−0.23 to 0.08) (n=31) | 0.03 (−0.15 to 0.21) (n=31) |
| HCCQ (1–7)* | 3.95 (1.50) (1.17–7.00) (n=39) | 5.46 (1.36) (2.00–7.00) (n=34) | 4.85 (1.69) (1.33–7.00) (n=36) | 1.35 (0.65 to 2.05) (n=31) | 1.01 (0.35 to 1.67) (n=32) |
| RASE (28–140)* | 100.16 (12.20) (78.00–128.00) (n=38) | 105.67 (13.36) (72.00–140.00) (n=33) | 104.32 (16.21) (72.00–135.00) (n=35) | 3.32 (−0.62 to 7.26) (n=31) | 4.80 (1.00 to 8.60) (n=32) |
*Higher scores indicate better outcome.
BRAF-MDQ, BRAF Multidimensional Questionnaire; HCCQ, Health Care Climate Questionnaire; MHAQ, Modified Health Assessment Questionnaire; RAID, Rheumatoid Arthritis Impact of Disease; RASE, Rheumatoid Arthritis Self-Efficacy Scale.