Table 3

Gap analysis

DomainOutcomeInterpretable measurement instrument(s) identified
Adverse eventsDeath
Surgical adverse events0 (N=55)
Economic impactCost of care
Employment status0 (N=5)
Life impactDependence
Falls0 (N=173)
Fatigue1 (N=207)
Mental health
Mobility
Neuromuscular functionArm strength
Balance
Bladder function
Faecal incontinence0 (N=308)
Finger/hand dexterity
Finger strength
Grip strength
Leg strength
Muscle tone and spasticity0 (N=39)
Neck mobility
Sensation
PainLocation
Intensity
Pain control
Perception
RadiologyAdjacent segment degeneration0 (N=69)
Cervical spine alignment0 (N=24)
Cord compression0 (N=69)
Cord signal change0 (N=24)
  • Elements with at least one interpretable instrument (see phase 2.1) are shaded green and will be published separately. Targeted searches of MEDLINE were performed for the remaining elements (ie, ‘gaps’, unshaded, see phase 2.2). For gaps within the domain of pain (shaded blue), the resources aggregated by Initiative on Methods, Measurement and Pain Assessment in Clinical Trials were deemed sufficient.79 The number of articles (N) screened is indicated for each gap. Notably, only one suitable resource was identified for ‘fatigue’.55