Table 1

Description of the studies included in the meta-analysis

First author, year	Journal	Patients	HbAlc, %	LGE definition	DM (type)	Mean age (years)	Duration of diabetes (years)	LVEF (%)	Follow-up duration (months)	Male	LGE(+)	Total events	Adjusted HR	Fibrosis type	Type design	Outcome	NOS
Bertheau et al 201621	Eur Radiol	61	7.2 (6.5–7.9)	Visual	1 and 2	67.5 (56.7–71.8)	19 (14–28)	56 (46–61)	70 (57–72)	31	17	8	Yes	Ischaemic	Prospective, single centre	MACCES	7
Heydari et al 201616	Circ Cardiovasc Imaging	173	7.9±1.8	2 SD	NR	61.7±11.9	NR	51.8±17.6	34.8±30	109	88	21	No	Ischaemic	Prospective, single centre	MACES	7
Elliott et al 20192	Diabetes Care	120	NR	Visual	1 and 2	52±13	17±11	63±9	46 (33–64)	65	23	19	Yes	Ischaemic	Prospective, two centres	MACES	9
Yoon et al 201319	Eur Radiol	120	7.4±1.5	Visual	2	67±9	11±11	63±6	27 (7–112)	83	18	10	No	Ischaemic	Retrospective, single centre	MACES	7
Giusca et al 20163	Eur Heart J Cardiovasc Imaging	328	NR	Visual	NR	67±11	NR	57.7±11.6	35 (23–51.6)	250	176	26	Yes	Ischaemic and nonischaemic	Prospective, multicentre	MACES	8
Bamberg et al 201320	Radiology	61	7.2 (6.5–7.9)	Visual	1 and 2	67.5 (56.7–71.8)	19 (14–28)	56 (46–61)	70 (57–72)	31	17	18	Yes	Ischaemic	Prospective, single centre	MACCES	7
Kwong et al 200817	Circulation	107	7.3±1.6	2 SD	NR	59±12	10.7±8.5	NR	17 (6–57)	67	30	38	Yes	Ischaemic	Prospective, single centre	MACCES	9
Yoon et al 201218	Radiology	151	7.4±1.6	Visual	NR	67±9	14±11	NR	30 (6–103)	113	58	24	No	Ischaemic	Retrospective, single centre	MACES	6

*Columns represent n (%) or mean±SD or median (IQR).
DM, diabetes mellitus; LGE, late gadolinium enhancement; LVEF, left ventricular ejection fraction; MACCEs, major adverse cardiac and cerebrovascular events; MACEs, major adverse cardiac events; NOS, Newcastle–Ottawa Scale; NR, not reported.