Table 2

Testing of plasma and dry blood spots for SARS-CoV-2 specific antibodies

PlasmaDry blood spots

  • BioPlex 2200 SARS-CoV-2 IgG Panel (Bio-Rad Laboratories (Canada), Mississauga, Canada)—differentiates IgG antibody levels to receptor-binding domain (RBD), spike 1 (S1), spike 2 (S2) and nucleocapsid (N) proteins

  • ARCHITECT SARS-CoV-2 IgG assay (Abbott, Illinois, USA)—qualitative antibody test against recombinant nucleocapsid protein

  • ARCHITECT AdviseDx SARS-CoV-2 IgG II (Abbott, Illinois, USA)—qualitative and semi-quantitative antibody test against spike protein (receptor binding domain of S1)

  • SARS-CoV-2 Surrogate Virus Neutralization Test (sVNT) Kit (RUO) (GenScript, Piscataway New Jersey, USA)—qualitative and semi-quantitative detection of SARS-CoV-2 neutralising antibodies

  • Neutralising SARS-CoV-2 antibody test (Inhouse assay, National Microbiology Laboratory)

  • BioPlex 2200 SARS-CoV-2 IgG Panel (Bio-Rad Laboratories (Canada), Mississauga, Canada)—differentiates IgG antibody levels to receptor-binding domain (RBD), spike 1 (S1), spike 2 (S2) and nucleocapsid (N) proteins