Schedule of tests
| Day | 0 | 3 | 8 | 15 | 29 |
| Clinical examination | X* | X | X* | ||
| RK39 RDT (blood)* | X | ||||
| Full blood count* | X | X | |||
| CD4 count (blood)* | X | X | |||
| GeneXpert for tuberculosis (TB)* | X | ||||
| Chest X-ray for TB* | X | ||||
| Urine antigen ELISA | X | X | X | X | X |
| qPCR on blood and skin microbiopsies | X | X | X | X | X |
| Peripheral blood buffy coat smear | X | X | X | X | X |
| Spleen parasitological confirmation* | X | X† | |||
| Bone marrow parasitological confirmation*‡ | X | X |
*Routine tests.
†In an unlikely event, a splenic aspiration is contraindicated on day 29, bone marrow aspirate test of cure will be conducted as per standard practice.
‡In patients who are contraindicated for splenic aspiration, a bone marrow aspirate will be taken for diagnosis and test of cure as per standard practice. These patients will be recruited to a pilot study.