Table 2

Schedule of tests

Day0381529
Clinical examinationX*XX*
RK39 RDT (blood)*X
Full blood count*XX
CD4 count (blood)*XX
GeneXpert for tuberculosis (TB)*X
Chest X-ray for TB*X
Urine antigen ELISAXXXXX
qPCR on blood and skin microbiopsiesXXXXX
Peripheral blood buffy coat smearXXXXX
Spleen parasitological confirmation*XX†
Bone marrow parasitological confirmation*‡XX
  • *Routine tests.

  • †In an unlikely event, a splenic aspiration is contraindicated on day 29, bone marrow aspirate test of cure will be conducted as per standard practice.

  • ‡In patients who are contraindicated for splenic aspiration, a bone marrow aspirate will be taken for diagnosis and test of cure as per standard practice. These patients will be recruited to a pilot study.