Table 1

Coprimary and secondary key performance indicators of ASIC

Coprimary key performance indicatorsSecondary key performance indicators

  • 1. Diagnostic rate, defined as the proportion of patients diagnosed with ARDS out of all monitored patients

1. Prevalence of organ dysfunction within 28 days after diagnosis of ARDS or ICU discharge (whatever occurs first), defined as days without need of following measures:

  • Mechanical ventilation

  • Use of vasopressors

  • Renal replacement therapy

2. Guideline adherence regarding lung-protective ventilation, defined as the percentage of time within 28 days after ARDS diagnosis or ICU discharge (whatever occurs first), during which the mechanical ventilation parameters fulfil the following criteria:

  • Tidal volume (Vt): ≤6 mL/kg KG (predicted)

  • Endinspiratory pressure (PEI): ≤30 cmH2O

  • Positive endexpiratory pressure (PEEP) ≥5 cmH2O

  • Driving pressure (Δ p=PEI PEEP) ≤15 cmH2O

2. Treatment-duration on ICU after ARDS diagnosis
3. Hospital mortality after ARDS diagnosis
4. Acceptance and usability of the ASIC app and the mobile device:

  1. Pre-Roll-In of the ASIC app.

  2. Post-Roll-In (6 months) of the ASIC app.

  • ARDS, acute respiratory distress syndrome; ICU, intensive care unit.