Crude and adjusted HR (95% CI) of mood disorder for spine fracture
| Characteristic | HR (95% CI) | |||
| Crude* | P value | Adjusted*† | P value | |
| Total (n=300 700) | ||||
| Mood disorder | 1.23 (1.17 to 1.29) | <0.001‡ | 1.10 (1.04 to 1.15) | <0.001‡ |
| Control | 1.00 | 1.00 | ||
| Participants with osteoporosis (n=67 060) | ||||
| Mood disorder | 1.15 (1.08 to 1.22) | <0.001‡ | 1.04 (0.98 to 1.10) | 0.220 |
| Control | 1.00 | 1.00 | ||
| Participants without osteoporosis (n=233 640) | ||||
| Mood disorder | 1.45 (1.32 to 1.59) | <0.001‡ | 1.25 (1.14 to 1.37) | <0.001‡ |
| Control | 1.00 | 1.00 | ||
*Stratified the model for age, income, region of residence and osteoporosis.
†Adjusted the model for the Charlson Comorbidity Index and history of Alzheimer’s dementia.
‡Cox proportional hazards regression model; significance at p<0.05.