Table 2

Crude and adjusted HR (95% CI) of mood disorder for spine fracture

CharacteristicHR (95% CI)
Crude*P valueAdjusted*†P value
Total (n=300 700)
 Mood disorder1.23 (1.17 to 1.29)<0.001‡1.10 (1.04 to 1.15)<0.001‡
 Control1.001.00
Participants with osteoporosis (n=67 060)
 Mood disorder1.15 (1.08 to 1.22)<0.001‡1.04 (0.98 to 1.10)0.220
 Control1.001.00
Participants without osteoporosis (n=233 640)
 Mood disorder1.45 (1.32 to 1.59)<0.001‡1.25 (1.14 to 1.37)<0.001‡
 Control1.001.00
  • *Stratified the model for age, income, region of residence and osteoporosis.

  • †Adjusted the model for the Charlson Comorbidity Index and history of Alzheimer’s dementia.

  • ‡Cox proportional hazards regression model; significance at p<0.05.