Characteristics of studies included in the meta-analysis
Study | Ethnic | CAD type | Assessment timing | Measurement of depression | Number of patients (depressed/non-depressed) | Outcome | Number of events (depressed/non-depressed) | Follow-up time (years) | NOS |
de Jager et al 17 | Netherlands | SA and ACS | 1 month after PCI | HADS | 528 (104/424) | All-cause mortality | 35/98 | 10 | 9 |
Wang et al 11 | China | SA and ACS | 2 weeks after PCI | HADS MINI | 400 (154/246) | MACE (all-cause mortality, non-fatal MI and revascularisation) | 42/32 | 3 | 9 |
Yu et al 13 | Korea | CAD | Baseline during hospitalisation 1 month after discharge | PHQ-9 | 211 (64/157) | MACE (rehospitalisation, reinfarction, revascularisation or cardiac death) | 13/21 11/23 | 1 | 7 |
Park et al 15 | Korea | CAD | 1–4 days after PCI | HADS | 133 (44/89) | Recurrent cardiac events (MI, ISR, revascularisation) | 11/7 | 1 | 6 |
van Dijk et al 12 | Netherlands | SA and ACS | 6 months after PCI | HADS | 1112 (276/836) | All-cause mortality | 122/262 | 10 | 9 |
Schmidt et al 14 | Brazil | SA and ACS | Baseline | BDI | 125 (31/94) | MACE (death, MI or TVR) | 6/13 | 1 | 7 |
Meyer et al 16 | Germany | Stable coronary heart disease | Before PCI | HADS | 470 (101/369) | All-cause mortality MACE (NR) | 11/33 16/57 | 2 and 5 | 9 |
Li et al 10 | China | CAD | Baseline during hospitalisation | SDS | 308 (112/196) | MACE (all-cause mortality, non-fatal MI and revascularisation) | 9/4 | 1 | 7 |
ACS, acute coronary syndrome; BDI, Beck Depression Inventory; CAD, coronary artery disease; HADS, Hospital Anxiety and Depression Scale; ISR, in-stent restenosis; MACE, major adverse cardiac events (the definitions differ according to the study and have been shown in the table); MI, myocardial infarction; MINI, Mini-International Neuropsychiatric Interview; NOS, Newcastle-Ottawa Scale; NR, not reported information; PCI, percutaneous coronary intervention; PHQ-9, Patient Health Questionnaire-9;SA, stable angina; SDS, Self-Rating Depression Scale; TVR, target vessel revascularisation.