Table 1

Characteristics of studies included in the meta-analysis

StudyEthnicCAD typeAssessment timingMeasurement of depressionNumber of patients (depressed/non-depressed)OutcomeNumber of events (depressed/non-depressed)Follow-up time (years)NOS
de Jager et al 17 NetherlandsSA and ACS1 month after PCIHADS528 (104/424)All-cause mortality35/98109
Wang et al 11 ChinaSA and ACS2 weeks after PCIHADS MINI400 (154/246)MACE (all-cause mortality, non-fatal MI and revascularisation)42/3239
Yu et al 13 KoreaCADBaseline during hospitalisation
1 month after discharge
PHQ-9211 (64/157)MACE (rehospitalisation, reinfarction, revascularisation or cardiac death)13/21
11/23
17
Park et al 15 KoreaCAD1–4 days after PCIHADS133 (44/89)Recurrent cardiac events (MI, ISR, revascularisation)11/716
van Dijk et al 12 NetherlandsSA and ACS6 months after PCIHADS1112 (276/836)All-cause mortality122/262109
Schmidt et al 14 BrazilSA and ACSBaselineBDI125 (31/94)MACE (death, MI or TVR)6/1317
Meyer et al 16 GermanyStable coronary heart diseaseBefore PCIHADS470 (101/369)All-cause mortality
MACE (NR)
11/33
16/57
2 and 59
Li et al 10 ChinaCADBaseline during hospitalisationSDS308 (112/196)MACE (all-cause mortality, non-fatal MI and revascularisation)9/417
  • ACS, acute coronary syndrome; BDI, Beck Depression Inventory; CAD, coronary artery disease; HADS, Hospital Anxiety and Depression Scale; ISR, in-stent restenosis; MACE, major adverse cardiac events (the definitions differ according to the study and have been shown in the table); MI, myocardial infarction; MINI, Mini-International Neuropsychiatric Interview; NOS, Newcastle-Ottawa Scale; NR, not reported information; PCI, percutaneous coronary intervention; PHQ-9, Patient Health Questionnaire-9;SA, stable angina; SDS, Self-Rating Depression Scale; TVR, target vessel revascularisation.