Table 2

Markers will be investigated in SIMPLE study

Target diseaseMarkers
Congestive heart failureMid-regional pro-atrial natriuretic peptide (MR-proANP)
Tuberculous pleurisySoluble Fas ligand; interleukin 27 (IL-27); C-X-C motif chemokine receptor 3 (CXCR3) ligands
Malignant diseasesSoluble B7-H4; human epididymis 4 (HE4); cancer ratio; Dickkopf-1 (DDK1)
Parapneumonic effusionPresepsin; pentraxin-3
  • SIMPLE, Study Investigating Markers in PLeural Effusion.