Markers will be investigated in SIMPLE study
| Target disease | Markers |
| Congestive heart failure | Mid-regional pro-atrial natriuretic peptide (MR-proANP) |
| Tuberculous pleurisy | Soluble Fas ligand; interleukin 27 (IL-27); C-X-C motif chemokine receptor 3 (CXCR3) ligands |
| Malignant diseases | Soluble B7-H4; human epididymis 4 (HE4); cancer ratio; Dickkopf-1 (DDK1) |
| Parapneumonic effusion | Presepsin; pentraxin-3 |
SIMPLE, Study Investigating Markers in PLeural Effusion.