Table 2

Definitions applied to estimation of absolute risk of primary fetal and infant outcomes

OutcomeNumeratorDenominator
MiscarriageNumber of miscarriages (pregnancy loss prior to 20 weeks gestation)Total number of pregnancies
Early fetal deathNumber of pregnancies lost between 20 and 27 weeks gestationTotal number of pregnancies carried to 20 weeks gestation
Late fetal deathNumber or pregnancies lost at or following 28 weeks gestationTotal number of pregnancies carried to 28 weeks gestation
MicrocephalyNumber of microcephaly casesTotal number of pregnancies carried to ≥24 weeks gestation, when microcephaly can be assessed by ultrasound in ZIKV-infected mothers,38 we will consider all pregnancies regardless of whether the pregnancy results in a live birth
  • ZIKV, Zika virus.