Table 4

Hyperoxaemia variables and adjusted ORs (95% CI) for secondary outcomes

VariableICU transfer*Respiratory failure†Cardiovascular dysfunction‡Hepatic dysfunction§Renal dysfunction¶Coagulation dysfunction**
358 (3.5)68 (0.7)386 (3.8)678 (8.7)983 (12.6)408 (5.0)
PaO2MAX 2.81†† (2.26–3.50)1.45 (0.85–2.47)1.39‡‡ (1.09–1.78)0.99 (0.74–1.33)0.95 (0.72–1.26)0.64‡‡ (0.43–0.94)
PaO2AVG 2.04†† (1.61–2.57)1.13 (0.63–2.01)1.13 (0.87–1.47)0.96 (0.70–1.34)1.13 (0.84–1.53)1.08 (0.74–1.59)
PaO2MED 1.51‡‡ (1.18–1.94)0.66 (0.34–1.30)1.02 (0.78–1.33)1.02 (0.74–1.40)0.97 (0.72–1.31)1.17 (0.81–1.69)
AUC72 4.03†† (3.25–5.01)2.40§§ (1.46–3.95)1.63§§ (1.29–2.07)1.53‡‡ (1.18–1.97)1.33‡‡ (1.05–1.68)0.67‡‡ (0.48–0.92)

  • *Adjusted for systolic blood pressure, heart rate, body temperature, consciousness and supplemental oxygen.

  • †Adjusted for body temperature and consciousness.

  • ‡Adjusted for age, sex, heart rate, SaO2, bilirubin and creatinine.

  • §Adjusted for age, sex, systolic blood pressure, breath rate, SaO2, consciousness, supplemental oxygen, bilirubin, platelet and initial PO2.

  • ¶Adjusted for NEWS, bilirubin, creatinine, platelet and initial PO2.

  • **Adjusted for sex, systolic blood pressure, breath rate, SaO2, consciousness, supplemental oxygen, bilirubin, platelet and initial PO2.

  • ††P<0.0001.

  • ‡‡P<0.05

  • §§P<0.001.

  • AUC72, area under the curve divided by elapsed time between ED arrival and the last result of PO2 within 72 hours; ICU, intensive care unit; PaO2MED, median value of PO2 within 72 hours; PO2, PaO2 of oxygen.