Summary of the conditions, participants and study locations of the 11 publications included in this review
Publication | Condition | Country | Number of participants | Age range (years) | |
Congenital heart disease (CHD) | Other acquired heart disease | ||||
Andersen et al,18 2008 | Long QT Syndrome | Norway | Adults (n=7): four women, three men | 23–76 (n=7) | |
Claessens et al,19 2005 | Moderate or severe heart defects, such as tetralogy of Fallot, univentricular heart, ventricular septal defect (VSD) and aortic valve stenosis, transposition of the great arteries | Belgium | Adult patients (n=12): six women; six men | 25–40 (n=12) | |
Dekker et al,22 2016 | Peripartum cardiomyopathy (PPCM) | USA | Adult women (n=92): first pregnancy (n=49) second pregnancy (n=24) third pregnancy (n=10) >4th higher pregnancy (n=8) unreported (n=1) | 17–−41 (n=92) | |
Gantt,21 1992 | Transposition of the great vessels, pulmonary atresia, atrial septal defect, double outlet right ventricle, pulmonary stenosis, truncus arteriosus, coarctation of the aorta | USA | Adolescent, young adults (n=13) | 13–15 (n=3) 16–18 (n=4) 19–21 (n=3) 22–28 (n=3) | |
Gantt,20 2002 | One woman with childhood rheumatic fever; one adolescent woman had a heart murmur only; all other women had CHDs of varying types and severity that had been surgically repaired or palliated | USA | Adults and children (n=22): 11 mothers and 11 daughters | 30–60 9–18 | |
Hess et al,26 2010 | PPCM | USA | Adult women (n=12): seven women did not have other children prior to the diagnosis | 19–34 (n=12) | |
Hess et al,27 2012 | PPCM | USA | Adults (n=156): 148 (95%) women with PPCM 8 (5%) husbands, mothers, sisters and grandmothers. | ~27 (n=156) | |
Ngu et al,25 2014 | Mild: pulmonary atresia, moderately large VSD, transposition of the great vessels, coarctation of aorta, bicuspid aortic valve, Ebstein’s anomaly of tricuspid valve Moderate: tetralogy of Fallot, mitral valve dysplasia, subaortic stenosis Severe: VSD, aortic valve stenosis, double outlet right ventricle | Australia | Women with (n=20) or without (n=2 0) CHD aged >18 years, who had ≥1 successful pregnancy. | 32.6 ± 5.3 Women with CHD 33.9±5.2 Women without CHD | |
Ngu et al,24 2014 | Mild: pulmonary atresia, moderately large VSD, transposition of the great vessels, coarctation of the aorta, bicuspid aortic valve, Ebstein’s anomaly of tricuspid valve Moderate: tetralogy of Fallot, mitral valve dysplasia, subaortic stenosis Severe: VSD, aortic valve stenosis, double outlet right ventricle | Australia | Women with mild CHD (n=10) with: one child (n=4) two children (n=4) three children (n=2). Women with moderate to severe CHD (n=10) with: one child (n=5); two children (n=3); three children (n=2). | 35.8±5.9 (n=10): women with mild CHD-mean age 28.9±3.5 (n=10): women with moderate to severe CHD | |
Patel, Berg et al,28 2016 | PPCM | Sweden | Adult women (n=19) | 28–46 (n=19)* | |
Patel, Schaufelberge et al,23 2016 | PPCM | Sweden | Women (n=19) | 28–46 (n= 19)* |
*Separate studies drawing on data from the same cohort of women.