Changes in intraocular pressure with ageing and changes in metabolic syndrome parameters: 10-year longitudinal study (n=15 747)
| Univariate analyses | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Explanatory variable | Coefficient | 95% CI | p Value | Coefficient | 95% CI | p Value |
| Sex, men | −0.35 | −0.39 to −0.32 | <0.0001 | −0.12 | −0.16 to −0.08 | <0.0001 |
| Ageing, +10 years | −0.73 | −0.77 to −0.69 | <0.0001 | −0.59 | −0.64 to −0.54 | <0.0001 |
| HDL-C, +1 mmol/L | +0.28 | 0.21 to 0.35 | <0.0001 | +0.42 | 0.35 to 0.49 | <0.0001 |
| (HDL-C, +10 mg/dL) | +0.073 | 0.055 to 0.090 | <0.0001 | +0.11 | 0.09 to 0.13 | <0.0001 |
| Triglyceride, +1 mmol/L | +0.095 | 0.077 to 0.11 | <0.0001 | +0.092 | 0.073 to 0.11 | <0.0001 |
| (Triglyceride, +10 mg/dL) | +0.011 | 0.0086 to 0.013 | <0.0001 | +0.010 | 0.008 to 0.012 | <0.0001 |
| SBP, +10 mm Hg | +0.16 | 0.15 to 0.17 | <0.0001 | +0.090 | 0.077 to 0.10 | <0.0001 |
| DBP, +10 mm Hg | +0.20 | 0.19 to 0.22 | <0.0001 | +0.085 | 0.067 to 0.10 | <0.0001 |
| FPG, +1 mmol/L | +0.042 | 0.021 to 0.063 | <0.0001 | +0.091 | 0.071 to 0.11 | <0.0001 |
| (FPG, +10 mg/dL) | +0.023 | 0.012 to 0.035 | <0.0001 | +0.051 | 0.039 to 0.062 | <0.0001 |
DBP, diastolic blood pressure; FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; SBP, systolic blood pressure.