Selected functional variants and inhibitor comedications in genes whose enzymes metabolise tamoxifen
| Gene | No of selected functional variants | SNPs | Inhibitor comedications |
| CYP2D6 | 5 | rs1065852, rs16947, rs3892097, rs28371706, rs28371725 | Bupropion, cinacalcet, fluoxetine, paroxetine, quinidine, duloxetine, sertraline, terbinafine, amiodarone, cimetidine, indinavir, nelfinavir, ritonavir, clarithromycin, itraconazole, ketoconazole, nefazodone, saquinavir, telithromycin, aprepitant, erythromycin, Fluconazole, verapamil, diltiazem, cimetidine, voriconazole |
| CYP3A | 1 | rs10273424 | |
| CYP3A5 | 1 | rs776746 | |
| CYP2C9 | 2 | rs1057910, rs1799853 | Fluconazole, amiodarone, voriconazole |
| CYP2C19 | 2 | rs12248560, rs4244285 | |
| CYP2B6 | 2 | rs3745274, rs8192709 | |
| CYP1A1 | 1 | rs1048943 | |
| SULT1A1 | 3 | rs1042157, rs1801030, rs9282861 | |
| SULT1E1 | 2 | rs3775775, rs3775778 | |
| UGT2B7 | 1 | rs7434332 | |
| UGT2B10 | 1 | rs294769 | |
| ABCC2 | 3 | rs3740065, rs717620, rs8187710 | |
| ABCG2 | 3 | rs1564481, rs2231164, rs2622604 | |
| ABCB1 | 4 | rs10248420, rs1045642, rs1128503, rs2032582 | |
| UGT2B15 | 1 | rs1902023 |