Results of studies validating diagnoses of breast cancer (first row) and surgical procedures (subsequent rows)
| # | Author/year | Algorithms invasive breast cancer | Sensitivity | Specificity | PPV | NPV |
| 1 | Solin et al 50 1994 | Diagnosis incident cases | – | – | 88 (85 to 91) | – |
| 2 | Solin 1994 | Mastectomy | – | – | 95 (92 to 98) | – |
| 3 | Solin 1994 | Partial mastectomy with lymphadenectomy | – | – | 96 (91 to 100) | – |
| 4 | Solin 1994 | Excision and lymphadenectomy | – | – | 100 (100 to 100) | – |
| 1 | Solin et al 51 1997 | Initial algorithm: diagnosis incident cases | – | – | 83 (78 to 89) | – |
| 2 | Solin 1997 | Initial algorithm: mastectomy | – | – | 95 (90 to 100) | – |
| 3 | Solin 1997 | Initial algorithm: partial mastectomy with lymphadenectomy | – | – | 95 (88 to 100) | – |
| 4 | Solin 1997 | Initial algorithm: excision and lymphadenectomy | – | – | 92 (83 to 100) | – |
| 5 | Solin 1997 | Best algorithm: diagnosis incident cases | – | – | 84 (79 to 90) | – |
| 6 | Solin 1997 | Best algorithm: mastectomy | – | – | 82 (76 to 88) | – |
| 7 | Solin 1997 | Best algorithm: partial mastectomy with lymphadenectomy | – | – | 84 (78 to 89) | – |
| 8 | Solin 1997 | Best algorithm: excision and lymphadenectomy | – | – | 84 (78 to 89) | – |
| 1 | McClish et al 46 1997 | incident cases identified in MEDPAR | 83 (82 to 84) | – | – | – |
| 2 | McClish 1997 | incident cases identified in VCR | 82 (81 to 83) | – | – | – |
| 3 | McClish 1997 | aggregated (VCR+MEDPAR) | 97 (96 to 97) | – | – | – |
| 4 | McClish 1997 | MEDPAR definitive surgical therapy | 80 (79 to 81) | – | – | – |
| 5 | McClish 1997 | VCR definitive surgical therapy | 87 (86 to 88) | – | – | – |
| 1 | Leung et al 45 1999 | Initial algorithm: diagnosis | – | – | 84 (82 to 87) | – |
| 2 | Leung 1999 | Mastectomy | – | – | 92 (90 to 95) | – |
| 3 | Leung 1999 | Partial mastectomy with lymphadenectomy | – | – | 98 (96 to 100) | – |
| 4 | Leung 1999 | Excision, breast biopsy or partial mastectomy plus lymphadenectomy | – | – | 92 (87 to 98) | – |
| 1 | Cooper et al 61 1999 | First set of analysis (increase in SE including in order inpatient other diagnosis, surgical, part B, etc): inpatient, first position diagnostic codes | 68 (68 to 69) | – | – | – |
| 2 | Cooper 1999 | First set of analysis: inpatient, surgical | 79 (79 to 79) | – | – | – |
| 3 | Cooper 1999 | First set of analysis: part B, first position | 91 (91 to 91) | – | – | – |
| 4 | Cooper 1999 | First set of analysis: part B, surgical | 94 (93 to 94) | – | – | – |
| 5 | Cooper 1999 | Second set of analysis (increase in SE including in order part B other diagnosis, surgical, inpatient, etc): part B, first position | 66 (66 to 66) | – | – | – |
| 6 | Cooper 1999 | Second set of analysis: part B, other diagnostic codes | 77 (77 to 77) | – | – | – |
| 7 | Cooper 1999 | Second set of analysis: part B, surgical | 81 (81 to 81) | – | – | – |
| 8 | Cooper 1999 | Second set of analysis: inpatient, first position | 91 (91 to 91) | – | – | – |
| 9 | Cooper 1999 | Second set of analysis: inpatient, surgical | 94 (93 to 94) | – | – | – |
| 1 | Freeman et al 42 2000 | Primary diagnosis: hospital inpatient in Medicare Provider Analysis (MEDPAR) | 68 (66 to 70) | – | 74 (72 to 76) | – |
| 2 | Freeman 2000 | Mastectomy hospital inpatient | 53 (51 to 56) | – | 73 | – |
| 3 | Freeman 2000 | Partial mastectomy hospital inpatient | 7 (4 to 11) | – | 64 | – |
| 4 | Freeman 2000 | Excisional biopsy hospital inpatient | 8 (5 to 12) | – | 56 | – |
| 5 | Incisional biopsy hospital inpatient | 8 (5 to 11) | – | 73 | – | |
| 1 | Ganry et al 54 2003 | Hospitalisation with breast cancer as primary diagnosis: mastectomy | – | – | 100 (100 to 100) | – |
| 2 | Ganry 2003 | Hospitalisation with breast cancer as primary diagnosis: partial mastectomy with lymphadenectomy | – | – | 100 (100 to 100) | – |
| 3 | Ganry 2003 | Hospitalisation with breast cancer as primary diagnosis: biopsy/excision plus the diagnosis of carcinoma | – | – | 100 (100 to 100) | – |
| 1 | Kemp et al 43 2013 | Diagnosis of invasive breast cancer | 86 (85 to 88) | 100 (100 to 100) | 86 (84 to 87) | 100 (100 to 100) |
| 2 | Kemp 2013 | Lumpectomy | 61 (59 to 63) | 99 (99 to 99) | 52 (50 to 54) | 99 (99 to 99) |
| 3 | Kemp 2013 | Mastectomy | 33 (31 to 35) | 100 (100 to 100) | 71 (68 to 74) | 99 (99 to 99) |
| 4 | Kemp 2013 | Lumpectomy OR mastectomy | 84 (83 to 86) | 99 (99 to 99) | 56 (55 to 58) | 100 (100 to 100) |
MEDPAR, Medicare Annual Demographic Files, the Medicare Provider Analysis and Review; NPV, negative predictive value; PPV, positive predictive value; VCR, Virginia Cancer Registry.