The health state cost parameters used in the Sheffield Type 1 Diabetes Policy Model
| Part A: seemingly unrelated regression functions for estimated costs in year 1 and ongoing based on REPOSE trial data (multivariate normal distributions*) | |||||||
| Annual cost of insulin and MDI consumables (year 1) | Annual cost of insulin and MDI consumables (ongoing) | Annual cost of DRC (year 1) | Annual cost of DRC (ongoing) | Annual cost of insulin pump and associated consumables (year 1) | Annual cost of insulin pump and associated consumables (ongoing) | Sources | |
| Multiplier for the baseline DRC cost (β1) | – | – | +0.11 | +0.03 | – | – | REPOSE trial data in year 1. (year 1 costs). REPOSE trial data in year 2. (ongoing costs). NHS reference costs.30 Pump costing survey. |
| Multiplier for the baseline insulin cost (β2) | +0.97 | +1.04 | – | – | – | – | |
| Multiplier for the baseline HbA1c (DCCT % scale) (β3) | +5.08 | +12.81 | −21.66 | +12.15 | – | – | |
| Receiving pump at the start of the year (β4) | −517.91 | −527.64 | +129.08 | +88.99 | +2056.11 | +2050.99 | |
| Switch from pump to MDI (β5) | +554.47 | +153.35 | +280.16 | −47.10 | −1143.68 | −905.03 | |
| Switch from MDI to pump (β6) | 0† | −353.27 | +733.95 | +201.93 | +804.57 | +1134.27 | |
| Constant (β0) | +381.77 | +324.53 | +415.46 | +299.80 | 0.00 | 0.00 | |