Table 4

Risk of bias summary for non-RCTs (ROBINS-I) 

PreinterventionAt interventionPostintervention
StudiesBias due to confoundingBias in selection of participants into the studyBias in classification of interventionsBias due to deviations from intended interventionsBias due to missing dataBias in measurement of outcomesBias in selection of the reported resultOverall risk of bias
Arraras 2008a16 MMMMMMUnclearLow or moderate risk if bias for all domains
Browall 200817 MMMSMMUnclearSerious risk of bias in at least one domain
Dees 200019 SSLMMMUnclearSerious risk of bias in at least one domain
Hurria 200620 MMLMLMUnclearLow or moderate risk if bias for all domains
Watters 200322 SMLMLMUnclearSerious risk of bias in at least one domain
Gállego Pérez-Larraya 201124 MMLMSSUnclearSerious risk of bias in at least one domain
Minniti 200926 MMLMLMUnclearLow or moderate risk if bias for all domains
Minniti 201327 MMLMSMUnclearSerious risk of bias in at least one domain
Mohile 201128 SMMUnclearLMUnclearSerious risk of bias in at least one domain
Arraras 2008b29 MSUnclearUnclearMMUnclearSerious risk of bias in at least one domain
Bouvier 200830 SMUnclearUnclearLMUnclearSerious risk of bias in at least one domain
Chang 201231 MMLMMMUnclearLow or moderate risk if bias for all domains
Caffo 200332 SSLUnclearMMUnclearSerious risk of bias in at least one domain
Park 201333 MMMMMMUnclearLow or moderate risk if bias for all domains
  • C, critical risk; L, low risk; M, moderate risk; S, serious risk.