Association of elevated depressive symptoms with mortality outcomes. Each participant contributes up to three time-variant CES-D measures
| Overall (N=29 491) | Self-reported general health as ‘excellent or very good’, n=13 711 | Self-reported general health as ‘poor, fair or good’, n=15 780 | |
| HR (95% CI) for categorical CES- D (score ≥ 4 v s < 4) | |||
| All-cause mortality | |||
| Events, n | 4581 | 1392 | 3189 |
| Crude | 1.66 (1.54 to 1.80) | 1.97 (1.66 to 2.33) | 1.30 (1.19 to 1.42) |
| Model 1* | 1.63 (1.50 to 1.76) | 1.74 (1.46 to 2.07) | 1.42 (1.29 to 1.55) |
| Model 2† | 1.42 (1.31 to 1.54) | 1.60 (1.34 to 1.90) | 1.30 (1.19 to 1.43) |
| Model 3‡ | 1.38 (1.27 to 1.49) | 1.57 (1.32 to 1.87) | 1.27 (1.16 to 1.39) |
| Model 4§ | 1.24 (1.13 to 1.35) | 1.53 (1.27 to 1.83) | 1.16 (1.05 to 1.28) |
| Model 5¶ | 1.24 (1.14 to 1.36) | 1.48 (1.27 to 1.78) | 1.17 (1.06 to 1.30) |
| Model 4 + CES-D × self-reported health | P value for the interaction term—0.005 | ||