Summary of the relative risks of all outcomes evaluated
Outcomes | Mild OSA (RR with 95% CI) | P value for mild OSA | Moderate OSA (RR with 95% CI) | P value for moderate OSA | Severe OSA (RR with 95% CI) | P value for severe OSA |
MACEs | 0.98 (0.87 to 1.11) | 0.741 | 1.16 (1.01 to 1.33) | 0.034 | 2.04 (1.56 to 2.66) | <0.001 |
CHD | 1.25 (0.95 to 1.66) | 0.117 | 1.38 (1.04 to 1.83) | 0.026 | 1.63 (1.18 to 2.26) | 0.003 |
Stroke | 1.29 (0.69 to 2.41) | 0.424 | 1.35 (0.82 to 2.23) | 0.245 | 2.15 (1.42 to 3.24) | <0.001 |
Cardiac death | 1.80 (0.68 to 4.76) | 0.236 | 1.11 (0.53 to 2.35) | 0.781 | 2.96 (1.45 to 6.01) | 0.003 |
All-cause mortality | 1.26 (0.77 to 2.07) | 0.354 | 1.04 (0.60 to 1.79) | 0.895 | 1.54 (1.21 to 1.97) | <0.001 |
Heart failure | 1.02 (0.78 to 1.34) | 0.868 | 1.07 (0.74 to 1.54) | 0.719 | 1.44 (0.94 to 2.21) | 0.097 |
CHD, coronary heart disease; MACE, major cardiovascular event; OSA, obstructive sleep apnoea; RR, relative risk.