Data collection time points for enrolled participants
| Time point | ||
| Baseline | Daily | PICU discharge |
| Age | Ventilation mode* | Date of discharge |
| Gender | Interventions for organ support† | Survival status |
| Weight | Hourly SpO2 values‡ | Discharge diagnosis |
| Acute diagnosis | – | – |
| Chronic diagnosis | – | – |
| Severity of gas exchange | – | – |
| Cause of respiratory failure | – | – |
| PIM2r score | – | – |
*Ventilation mode including FiO2 and mean airway pressure.
†Including use of vasoactive drugs, ECMO, blood transfusion, renal support and neuromuscular blocker or sedative drug infusions.
‡Hourly SpO2 values for first 24 hours, then 4 hourly until day 6 postrandomisation and 12 hourly thereafter until the end of mechanical ventilation.
ECMO, extracorporeal membrane oxygenation; FiO2, fraction of inspired oxygen; PICU, paediatric intensive care unit; PIM2r, paediatric index of mortality 2 recalibated; SpO2, peripheral oxygen saturations.