Table 3

Associations of mortality risk factors with outcome of age acceleration (years) at 53 for NSHD participants*

Variable	Level	Blood (n=152)			Buccal (n=790)
Variable	Level	Regression coefficient (difference per year AA)	95% CI	p Value	Regression coefficient (difference per year AA)	95% CI	p Value
Height (cm)		−0.017	−0.085 to 0.051	0.63	−0.011	−0.14 to 0.11	0.86
BMI 53 (kg/m²)		0.085	0.014 to 0.16	0.02	0.044	−0.065 to 0.15	0.42
Smoking	Current	Reference		0.001	Reference		0.42
	Ex-smoker	1.88	0.85 to 2.91		0.83	−0.99 to 2.66
	Never	1.86	0.76 to 2.95		−0.16	−2.17 to 1.85
Childhood SEP	Professional	Reference		0.80	Reference		0.56
	Intermediate	−0.73	−2.44 to 0.99		−1.30	−4.01 to 1.40
	Skilled (non-manual)	−0.81	−2.59 to 0.97		−0.48	−3.24 to 2.27
	Skilled (manual)	−0.25	−1.89 to 1.38		−1.24	−3.88 to 1.39
	Partly skilled	−0.94	−2.67 to 0.79		−0.11	−2.90 to 2.67
	Unskilled	−0.40	−2.57 to 1.78		1.39	−2.40 to 5.17
Adult SEP	Professional	Reference		0.62	Reference		0.35
	Intermediate	0.95	−2.11 to 4.01		−1.65	−10.27 to 6.97
	Skilled (non-manual)	0.95	−2.10 to 4.00		−1.95	−10.59 to 6.69
	Skilled (manual)	1.35	−1.97 to 4.68		−0.25	−9.13 to 8.63
	Partly skilled	0.032	−3.12 to 3.18		−3.41	−12.31 to 5.50
	Unskilled	0.52	−2.85 to 3.89		0.24	−8.73 to 9.22
Education	None	Reference		0.78	Reference		0.64
	Vocational	0.16	−1.65 to 1.98		−1.25	−4.72 to 2.22
	Sub-GCSE	1.20	−0.73 to 3.14		−1.74	−5.21 to 1.73
	O level	0.41	−0.63 to 1.45		−1.02	−2.90 to 0.86
	A level	−0.53	−1.81 to 0.75		−1.97	−4.29 to 0.35
	Burham A2	0.55	−0.91 to 2.00		−1.43	−3.66 to 0.81
	Degree	−0.28	−2.36 to 1.81		−2.01	−5.73 to 1.71
	Postgraduate	−0.81	−8.73 to 7.11		0.84	−0.38 to 2.06

*AA, age acceleration; BMI, body mass index; GCSE, General Certificate of Secondary Education; NSHD, National Survey of Health and Development; SEP, socioeconomic position.