Table 2

Association of age acceleration with changes in physical capability from age 53 to 64 in NSHD participants

Variable	Model*	Blood (n=152)			Buccal (n=790)
Variable	Model*	Regression coefficient (difference per year AA)	95% CI	p Value	Regression coefficient (difference per year AA)	95% CI	p Value
Grip strength (kg)	Unadjusted	−0.34	−0.70 to 0.01	0.06	−0.02	−0.16 to 0.12	0.73
	Adjusted for age, height, BMI	−0.33	−0.69 to 0.02	0.06	−0.03	−0.17 to 0.12	0.73
	Adjusted for height, BMI, smoking, education and SEP	−0.42	−0.82, to 0.03	0.03	−0.07	−0.22 to 0.08	0.35
Chair rise speed (stands/min)	Unadjusted	0.20	−0.23 to 0.62	0.37	−0.03	−0.17 to 0.12	0.70
	Adjusted for age, height, BMI	0.19	−0.24 to 0.62	0.38	−0.04	−0.19 to 0.10	0.58
	Adjusted for height, BMI, smoking, education and SEP	0.06	−0.40 to 0.52	0.80	−0.05	−0.20 to 0.10	0.53
Balance time, eyes closed (log-seconds)	Unadjusted	−0.01	−0.04 to 0.02	0.38	−0.001	−0.011 to 0.010	0.92
	Adjusted for age, height, BMI	−0.01	−0.04 to 0.02	0.39	−0.002	−0.012 to 0.009	0.76
	Adjusted for height, BMI, smoking, education and SEP	−0.01	−0.04 to 0.02	0.55	−0.002	−0.012 to 0.009	0.73
Composite score	Unadjusted	−0.01	−0.028 to 0.003	0.10	0.001	−0.005 to 0.007	0.77
	Adjusted for age, height, BMI	−0.01	−0.028 to 0.003	0.11	0.000	−0.005 to 0.006	0.87
	Adjusted for height, BMI, smoking, education and SEP	−0.01	−0.03 to 0.01	0.16	−0.001	−0.007 to 0.005	0.68

AA, age acceleration; BMI, body mass index; SEP, socioeconomic position.
*For each of the four physical capability outcome measures, we ran three models, first unadjusted, then adjusted for height and BMI, then adjusted for height, BMI, smoking, education and both adult and childhood SEP.