Table 1

Characteristics of included studies

StudyCountryYearN (% male)Age rangeRace/ethnicityEye examinedPupil dilationFundus photographyImage gradingOCT used
BDESUSA1987–1988480243–84CaucasianBothYes30°; stereo; >3 fields; filmReading centre at University of WisconsinNo
Beixinjing*China2010–20113326 (44.5)50–98AsianBothYes45°; non-stereo; two fields; digitalOphthalmologistsNo
BMESAustralia1992–19933490 (43.8) 49CaucasianBothYes30°; stereo; six fields; filmReading centre at University of SydneyNo
FunagataJapan2000–20021543 (43.4) 35AsianRight eyeNo45°; non-stereo; one field; filmReading centre at University of SydneyNo
HESChina2006–20076565 (46.7) 30AsianBothPart of*45°; non-stereo; two fields; digitalOphthalmologistsYes
HisayamaJapan19981765 (38.5) 40AsianBothYes45°; non-stereo; one field; filmOphthalmologistsNo
JiangningChina2012–20132005 (43.7) 50AsianBothNo45°; non-stereo; >2 fields; digitalTrained gradersYes
LALESUSA2000–20035982 (42.0) 40HispanicBothYes30°degree; stereo, three fields; filmReading centre at University of WisconsinNo
MESAUSA2002–20045960 (47.9)45–84White, black; Asian; HispanicBothNo45°; non-stereo; two fields; digitalReading centre at University of WisconsinNo
SCESSingapore2009–2011335340–80AsianBothYes45°; non-stereo; two fields; digitalReading centre at University of SydneyNo
SiMESSingapore2004–20063265 (48.1)40–80AsianBothYes45°; non-stereo; two fields; digitalReading centre at University of SydneyNo
SINDISingapore2007–20093328 (50.2)40–80AsianBothYesNon-stereo; two fields; digitalReading centre at University of SydneyNo
VIPAustralia1992–19974313 (47.0) 40CaucasianBothYes30°; stereo; two fields; filmReading centre at University of SydneyNo
  • *Data only available for primary ERMs.

  • BDES, Beaver Dam Eye Study; BMES, Blue Mountains Eye Study; HES, Handan Eye Study; LALES, Los Angeles Latino Eye Study; MESA, Multi-Ethnic Study of Atherosclerosis; OCT, optical coherence tomography; SCES, Singapore Chinese Eye Study; SiMES, Singapore Malay Eye Study; SINDI, Singapore Indian Eye study; VIP, Visual Impairment Project.