Baseline characteristics for extracted SMI population who were free of cardiovascular disease (CVD) and aged 30–74 years and sample of 1000 patients, where continuous variables are reported as mean (SD) and discrete variables are reported as n (%)
| Baseline characteristics | Total population | Sample of population |
| n | 33 026 | 1000 |
| Age, mean (SD), years | 50.3 (12.0) | 50.2 (12.0) |
| Female, n (%) | 16 155 (48.7) | 513 (51.3) |
| Type of SMI, n (%) | ||
| Schizophrenia | 11 495 (34.8) | 335 (33.5) |
| Bipolar disorder | 8822 (26.7) | 256 (25.6) |
| Other non-organic psychotic disorders | 9098 (27.6) | 313 (31.3) |
| On SMI registry but no diagnoses | 3611 (10.9) | 96 (9.6) |
| SBP, mean (SD), mm Hg | 128 (16) | 128 (16) |
| Antihypertensive therapy, n (%) | 5402 (16.4) | 164 (16.4) |
| Total cholesterol, mean (SD), mmol/L | 5.4 (1.1) | 5.3 (1.0) |
| HDL cholesterol, mean (SD), mmol/L | 1.3 (0.4) | 1.4 (0.4) |
| Lipid-lowering therapy, n (%) | 3545 (10.7) | 97 (9.7) |
| Weight, mean (SD), kg | 80.0 (18.9) | 79.5 (18.8) |
| Height, mean (SD), m | 1.7 (0.1) | 1.7 (0.1) |
| BMI, mean (SD), kg/m2 | 28.0 (6.1) | 27.9 (6.0) |
| Diabetes, n (%) | 2412 (7.3) | 74 (7.4) |
| Smoking status, n (%) | ||
| Non-smoker | 11 474 (34.7) | 355 (35.5) |
| Ex-smoker | 3726 (11.3) | 100 (10.0) |
| Current smoker | 17 826 (54.0) | 545 (54.5) |
| History of heavy drinking, n (%) | 4706 (14.3) | 139 (13.9) |
| Depression, n (%) | 21 190 (64.2) | 633 (66.3) |
| Antidepressant therapy, n (%) | 13 055 (39.5) | 377 (37.7) |
| First-generation antipsychotic therapy, n (%) | 4982 (15.1) | 133 (13.3) |
| Second-generation antipsychotic therapy, n (%) | 10 691 (32.4) | 311 (31.1) |
| Townsend score of deprivation*, n (%) | ||
| 1 | 4886 (14.8) | 143 (14.3) |
| 2 | 5332 (16.2) | 158 (15.8) |
| 3 | 6639 (20.1) | 183 (18.3) |
| 4 | 8048 (24.4) | 269 (26.9) |
| 5 | 8121 (24.6) | 247 (24.7) |
| Calendar year†, mean (SD) | 2007.7 (3.5) | 2007.7 (3.5) |
*Townsend score of deprivation is an index made up of unemployment, overcrowding, non-car ownership and non-home ownership, where 1 represents lower degree of deprivation and 5 represents higher degree of deprivation.
†Calendar year refers to the calendar year in which the baseline data were collected to account for any time trends.
BMI, body mass index; HDL, high-density lipoprotein; SBP, systolic blood pressure; SMI, severe mental illness.