Table 3

Baseline and 5-week active extension deficit for the joints that had worsened by ≥20° at the 2-year measurement (compared with the 5-week measurement) and the joints that had not worsened between these two measurement times; hands treated with a single collagenase injection

Worsened ≥20° after the 5-week postinjection measurementNot worsened after the 5-week postinjection measurementp Value
MCP, n738
 Baseline60 (40, 65)55 (40, 70)0.87
 5-week0 (0, 0)0 (0, 10)0.57
PIP, n738
 Baseline60 (30, 75)10 (0, 40)0.017
 5 week15 (15, 55)0 (0, 15)0.004
  • Values are median (25th, 75th centiles) active extension deficit.

  • MCP, metatarsophalangeal joint; PIP, proximal interphalangeal joint.