Table 1

Study and patient characteristics

Study, year	Years	Patients enrolled	Cancer type	Age (TTD vs PC)	TTD	PC offered in addition to TTD	PC	Expected median survival <6 months
Bellmunt, 2009	2003–2006	337	Urothelial	NR	Chemotherapy	Yes	Pain medication, palliative chemotherapy, supportive care, antibiotics, corticosteroids	Yes
Cartei, 1993	NR	102	Lung	Median (range): 57 (39–71) vs 56 (41–73)	Chemotherapy	Yes	Pain medication, radiotherapy, supportive care	Yes
Ciuleanu, 2009	2004–2006	303	Pancreatic	Median (range): 58 (27–78) vs 57 (29–80)	Chemotherapy	Yes	Pain medication, supportive care, appetite stimulators	Yes
De Marinis, 1999a	1990–1993	61	Lung	NR	Chemotherapy	Unclear	Pain medication, radiotherapy, steroids, progestins	Yes
De Marinis, 1999b	1990–1993	63	Lung	NR	Chemotherapy	Unclear	Pain medication, radiotherapy, steroids, progestins	Yes
De Marinis, 1999c	1990–1993	64	Lung	NR	Chemotherapy	Unclear	Pain medication, radiotherapy, steroids, progestins	Yes
Lissoni, 1994a	NR	50	Pancreatic	Median (range): 56 (39–71) vs 57 (50–74)	Chemotherapy	Yes	Pain medication, supportive care, steroids, antiemetics, ansioliticos	Yes
Lissoni, 1994b	NR	50	Solid tumors	Median (range): 56 (38–72) vs 58 (42–71)	Drug therapy	Yes	Supportive care	Yes
Ranson, 2000	1995–1997	157	Lung	Median (range): 65 (37–78) vs 64 (23–82)	Chemotherapy	Yes	Radiotherapy, supportive care, corticosteroids, antibiotics, antiemetics	Yes
Schmid, 1993a	1987–1989	87	Esophageal	Median: 55 vs 53	Radiotherapy	Unclear	Intubation only	Yes
Schmid, 1993b	1987–1989	86	Esophageal	Median: 55 vs 53	Chemotherapy	Unclear	Intubation only	Yes
Selawry, 1977a	NR	150	Lung	Median: 62 vs 59	Chemotherapy	Unclear	NR	Yes
Selawry, 1977b	NR	152	Lung	Median: 59 vs 59	Chemotherapy	Unclear	NR	Yes
Xinopoulos, 2008	NR	73	Pancreatic	Mean (range): 66.5 (59–73) vs 66.6 (58–73)	Chemotherapy	Unclear	Plastic biliary endoprosthesis placement as needed	Yes

NR, not reported; PC, palliative care; TTD, treatment targeted at underlying disease.