General characteristics of the included systematic reviews (N=200)
| Overall (N=200) | Cochrane (N=100) | Non-Cochrane (N=100) | p Value* | |
|---|---|---|---|---|
| Number of systematic review authors; median (IQR) | 5 (4–7) | 5 (4–6) | 6 (3–8) | 0.018 |
| Number of included trials; median (IQR) | 7 (2–14) | 7 (2–13) | 7 (2–15) | 0.220 |
| Number of randomised participants reported by the included trials; median (IQR) | 832 (222–2848) | 800 (191–2294) | 932 (261–4257) | 0.158 |
| Type of intervention | ||||
| Pharmacological | 98 (49%) | 49 (49%) | 49 (49%) | 0.250 |
| Surgical/invasive procedure | 55 (28%) | 23 (23%) | 32 (32%) | |
| Lifestyle intervention | 12 (6%) | 5 (5%) | 7 (7%) | |
| Rehabilitation | 7 (4%) | 3 (3%) | 4 (4%) | |
| Screening/diagnostic intervention | 5 (3%) | 4 (4%) | 1 (1%) | |
| Psychotherapeutic intervention | 13 (7%) | 10 (10%) | 3 (3%) | |
| Other | 10 (5%) | 6 (6%) | 4 (4%) | |
| Type of control | ||||
| Active control (as opposed to non-active control) | 85 (43%) | 31 (31%) | 54 (54%) | 0.001 |
| Tools used to evaluate risk of bias | ||||
| Cochrane risk of bias tool | 148 (74%) | 98 (98%) | 50 (50%) | <0.0001 |
| Revised Cochrane risk of bias tool | 0 (0%) | 0 (0%) | 0 (0%) | |
| Jadad's scale | 6 (3%) | 0 (0%) | 6 (6%) | |
| Other tool | 17 (9%) | 1 (1%) | 16 (16%) | |
| Not done | 29 (15%) | 1 (1%) | 28 (28%) | |
| Systems used to evaluate the quality of evidence by outcome | ||||
| GRADE | 79 (40%) | 71 (71%) | 8 (8%) | <0.0001 |
| Other system | 7 (4%) | 0 (0%) | 7 (7%) | |
| Not done | 114 (57%) | 29 (29%) | 85 (85%) | |
*p Value for the difference between Cochrane and non-Cochrane systematic reviews.