Table 5

Multivariate analyses for the associations of changes in intraocular pressure with ageing and changes in metabolic syndrome parameters.

Explanatory variable	Sensitivity analysis (1), n=15 747			Sensitivity analysis (2), n=5261
Explanatory variable	Coefficient	95% CI	p Value	Coefficient	95% CI	p Value
Sex, men	−0.12	−0.16 to 0.08	<0.0001	−0.092	−0.16 to −0.02	0.01
Ageing, +10 years	−0.59	−0.64 to −0.55	<0.0001	−0.74	−0.83 to −0.64	<0.0001
HDL-C, +1 mmol/L	+0.42	0.35 to 0.49	<0.0001	+0.44	0.30 to 0.57	<0.0001
(HDL-C, +10 mg/dL)	+0.11	0.09 to 0.13	<0.0001	+0.11	0.08 to 0.15	<0.0001
Triglyceride, +1 mmol/L	+0.091	0.073 to 0.11	<0.0001	+0.096	0.065 to 0.13	<0.0001
(Triglyceride, +10 mg/dL)	+0.010	0.008 to 0.012	<0.0001	+0.011	0.007 to 0.014	<0.0001
SBP, +10 mm Hg	+0.091	0.079 to 0.10	<0.0001	+0.083	0.054 to 0.11	<0.0001
DBP, +10 mm Hg	+0.085	0.067 to 0.10	<0.0001	+0.073	0.036 to 0.11	<0.0001
FPG, +1 mmol/L	+0.091	0.070 to 0.11	<0.0001	+0.15	0.10 to 0.20	<0.0001
(FPG, +10 mg/dL)	+0.050	0.039 to 0.062	<0.0001	+0.085	0.058 to 0.11	<0.0001

(1) Residents underwent health check-ups 3–20 times during 10 years. (2) Residents aged 19–44 underwent health check-ups once per year during 10 years.
DBP, diastolic blood pressure; FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; SBP, systolic blood pressure.