Table 1

Descriptive characteristics of included MAs

CategoryAll meta-analyses n=607
Total number of journals265
Funding source (yes)
 Government173 (28.5)
 Industrial0 (0)
 Other39 (6.3)
Common ICD-10
 Neoplasms261 (43)
 Diseases of the digestive system26 (4.3)
 Certain infectious and parasitic diseases28 (4.6)
 Disease of the circulatory system103 (17)
 Diseases of the musculoskeletal system and connective tissue14 (2.3)
 Diseases of the blood and blood forming organs and immune mechanism12 (1.9)
 Endocrine, nutritional and metabolic diseases34 (5.6)
 Diseases of the respiratory system16 (2.6)
 Diseases of the genitourinary system14 (2.3)
 Congenital malformations, deformations and chromosomal abnormalities3 (0.5)
 Injury, poisoning and certain other consequences of external causes61 (10.1)
 Pregnancy, childbirth and puerperium22 (3.6)
 Certain conditions originating in the perinatal period6 (0.9)
 Diseases of the eye and adnexa7 (1.2)
Number of authors, median (IQR)4 (1–11)
Number of included studies, median (IQR)
 Cohort, n=2413 (2–215)
 Case–controlled, n=48812 (2–90)
 Cohort + case–controlled, n=6511 (1–189)
 Cross-sectional, n=1016 (2–63)
Number of participants in included studies, median (IQR)
 Cohort, n=89561 279 (76–7 069 228)
 Case–controlled, n=5534575 (72–105 293)
 Cross-sectional, n=1078 (3–11 215)
Types of clinical study (yes)
 Therapy31 (5.1)
 Aetiology576 (94.9)
Types of models in included studies (yes)
 Fixed model107 (17.6)
 Random model164 (27.2)
 Not reported336 (55.2)
Indexed in CSCD, yes n (%)18.9
Update of a previous review: yes n (%)0 (0)
  • CSCD, Chinese Science Citation Database; ICD-10, International Classification of Diseases 10th edition; MA, meta-analyses.