RT Journal Article SR Electronic T1 The neurophysiological effects of dry needling in patients with upper trapezius myofascial trigger points: study protocol of a controlled clinical trial JF BMJ Open JO BMJ Open FD British Medical Journal Publishing Group SP e002825 DO 10.1136/bmjopen-2013-002825 VO 3 IS 5 A1 Abbaszadeh-Amirdehi, Maryam A1 Ansari, Noureddin Nakhostin A1 Naghdi, Soofia A1 Olyaei, Gholamreza A1 Nourbakhsh, Mohammad Reza YR 2013 UL http://bmjopen.bmj.com/content/3/5/e002825.abstract AB Introduction Dry needling (DN) is an effective method for the treatment of myofascial trigger points (MTrPs). There is no report on the neurophysiological effects of DN in patients with MTrPs. The aim of the present study will be to assess the immediate neurophysiological efficacy of deep DN in patients with upper trapezius MTrPs. Methods and analysis A prospective, controlled clinical trial was designed to include patients with upper trapezius MTrPs and volunteered healthy participants to receive one session of DN. The primary outcome measures are neuromuscular junction response and sympathetic skin response. The secondary outcomes are pain intensity and pressure pain threshold. Data will be collected at baseline and immediately after intervention. Ethics and dissemination This study protocol has been approved by the Research Council, School of Rehabilitation and the Ethics Committee of Tehran University of Medical Sciences. The results of the study will be disseminated in a peer-reviewed journal and presented at international congresses.