PT - JOURNAL ARTICLE AU - Sørensen, Lin AU - Jensen, Daniel A AU - Lykkebø, Amalie AU - Adolfsdottir, Steinunn AU - Holmen, Nina AU - Becker, Stephen P AU - Flo-Groeneboom, Elisabeth TI - The relationship between emotion dysregulation and sleep in children and adolescents with ADHD: protocol for a systematic review AID - 10.1136/bmjopen-2025-099096 DP - 2025 May 01 TA - BMJ Open PG - e099096 VI - 15 IP - 5 4099 - http://bmjopen.bmj.com/content/15/5/e099096.short 4100 - http://bmjopen.bmj.com/content/15/5/e099096.full SO - BMJ Open2025 May 01; 15 AB - Introduction Over half of children and adolescents with attention-deficit/hyperactivity disorder (ADHD) have difficulties with emotion dysregulation (EDR) and/or sleep, yet the interrelations between emotional regulation and sleep are not well-characterised in this population. This systematic review will address the relationship between these difficulties and investigate whether specific aspects of EDR are more strongly related to sleep problems in youth with ADHD.Methods and analysis We will adhere to the Preferred Reporting Items for Systematic Reviews and Meta-analysis guideline for systematic reviews. A wide set of electronic databases will be searched for peer-reviewed quantitative studies investigating the relationship between EDR and sleep in children and adolescents (ages 5 to 18 years) with ADHD. In addition, the reference list of all studies will be searched for other relevant studies, and Scopus will be used to search for citations of the included studies. We will also contact experts in the field to request published and unpublished studies. The primary outcome will be the effect size of the relationship between EDR and sleep in children and adolescents with ADHD. We will look at EDR and sleep broadly and also consider the multifaceted nature of both terms. Secondary outcomes will include which facets of EDR and sleep have been measured and how they have been measured, developmental differences between children and adolescents with ADHD and how—and the extent to which—studies controlled for the use of CNS medications and cooccurring disorders in their study design and/or statistical analyses. The quality and risk of bias of the included studies will be assessed using the Mixed Methods Appraisal Tool.Ethics and dissemination This protocol is for a review of studies and does not involve any new data collection and therefore does not need ethical or human subjects approval. The results will be presented at international conferences and in a peer-reviewed journal.PROSPERO registration number CRD42024612984.