PT  - JOURNAL ARTICLE
AU  - Zhao, Yi
AU  - Teh, Jhia Jiat
AU  - Kung, Victor
AU  - Mallappa, Sreelakshmi
TI  - Bowel ischaemia in COVID-19 infection: a scoping review protocol
AID  - 10.1136/bmjopen-2021-060566
DP  - 2022 Sep 01
TA  - BMJ Open
PG  - e060566
VI  - 12
IP  - 9
4099  - http://bmjopen.bmj.com/content/12/9/e060566.short
4100  - http://bmjopen.bmj.com/content/12/9/e060566.full
SO  - BMJ Open2022 Sep 01; 12
AB  - Introduction COVID-19 disease was declared as a pandemic by WHO since March 2020 and can have a myriad of clinical presentations affecting various organ systems. Patients with COVID-19 are known to have an increased risk of thromboembolism, including cardiovascular, pulmonary and cerebral ischaemic events. However, an increasing number of case studies have reported that COVID-19 infection is also associated with gastrointestinal ischaemia. This scoping review aims to collate the current evidence of COVID-19-related gastrointestinal ischaemia and raise awareness among healthcare professionals of this lesser known, but serious, non-pulmonary complication of COVID-19 infection.Methods The proposed scoping review will be conducted as per the Arksey and O’Malley methodological framework (2005) the Joanna Briggs Institute methodology for scoping reviews. A systematic search will be undertaken on different databases including EMBASE, PubMed and MEDLINE. Two independent reviewers will screen titles, abstracts and full-text articles according to the inclusion criteria and extract relevant data from the included articles. Results will be presented in a tabular form with a narrative discussion.Ethics and dissemination Ethical approval will not be required for this scoping review. This scoping review will provide an extensive overview of the association between COVID-19 infection and bowel ischaemia. Further ethical and methodological challenges will also be discussed in our findings to define a new research agenda. Findings will be disseminated through peer-reviewed publications and presentations at both national and international conferences.