RT Journal Article SR Electronic T1 Association of acculturation with cardiac structure and function among Hispanics/Latinos: a cross-sectional analysis of the echocardiographic study of Latinos JF BMJ Open JO BMJ Open FD British Medical Journal Publishing Group SP e028729 DO 10.1136/bmjopen-2018-028729 VO 9 IS 11 A1 López, Lenny A1 Swett, Katrina A1 Rodriguez, Fátima A1 Kizer, Jorge R A1 Penedo, Frank A1 Gallo, Linda A1 Allison, Matthew A1 Arguelles, William A1 Gonzalez, Franklyn A1 Kaplan, Robert C A1 Rodriguez, Carlos J YR 2019 UL http://bmjopen.bmj.com/content/9/11/e028729.abstract AB Objective Hispanics/Latinos, the largest immigrant population in the USA, undergo the process of acculturation and have a large burden of heart failure risk. Few studies have examined the association of acculturation on cardiac structure and function.Design Cross-sectional.Setting The Echocardiographic Study of Latinos.Participants 1818 Hispanic adult participants with baseline echocardiographic assessment and acculturation measured by the Short Acculturation Scale, nativity, age at immigration, length of US residence, generational status and language.Primary and secondary outcome measures Echocardiographic assessment of left atrial volume index (LAVI), left ventricular mass index (LVMI), early diastolic transmitral inflow and mitral annular velocities.Results The study population was predominantly Spanish-speaking and foreign-born with mean residence in the US of 22.7 years, mean age of 56.4 years; 50% had hypertension, 28% had diabetes and 44% had a body mass index >30 kg/m2. Multivariable analyses demonstrated higher LAVI with increasing years of US residence. Foreign-born and first-generation participants had higher E/e′ but lower LAVI and e′ velocities compared with the second generation. Higher acculturation and income >$20K were associated with higher LVMI, LAVI and E/e′ but lower e′ velocities. Preferential Spanish-speakers with an income <$20K had a higher E/e′.Conclusions Acculturation was associated with abnormal cardiac structure and function, with some effect modification by socioeconomic status.