RT Journal Article SR Electronic T1 Uptake and efficacy of a systematic intensive smoking cessation intervention using motivational interviewing for smokers hospitalised for an acute coronary syndrome: a multicentre before–after study with parallel group comparisons JF BMJ Open JO BMJ Open FD British Medical Journal Publishing Group SP e011520 DO 10.1136/bmjopen-2016-011520 VO 6 IS 9 A1 Auer, Reto A1 Gencer, Baris A1 Tango, Rodrigo A1 Nanchen, David A1 Matter, Christian M A1 Lüscher, Thomas Felix A1 Windecker, Stephan A1 Mach, François A1 Cornuz, Jacques A1 Humair, Jean-Paul A1 Rodondi, Nicolas YR 2016 UL http://bmjopen.bmj.com/content/6/9/e011520.abstract AB Objectives To compare the efficacy of a proactive approach with a reactive approach to offer intensive smoking cessation intervention using motivational interviewing (MI).Design Before–after comparison in 2 academic hospitals with parallel comparisons in 2 control hospitals.Setting Academic hospitals in Switzerland.Participants Smokers hospitalised for an acute coronary syndrome (ACS).Intervention In the intervention hospitals during the intervention phase, a resident physician trained in MI systematically offered counselling to all smokers admitted for ACS, followed by 4 telephone counselling sessions over 2 months by a nurse trained in MI. In the observation phase, the in-hospital intervention was offered only to patients whose clinicians requested a smoking cessation intervention. In the control hospitals, no intensive smoking cessation intervention was offered.Primary and secondary outcomes The primary outcome was 1 week smoking abstinence (point prevalence) at 12 months. Secondary outcomes were the number of smokers who received the in-hospital smoking cessation intervention and the duration of the intervention.Results In the intervention centres during the intervention phase, 87% of smokers (N=193/225) received a smoking cessation intervention compared to 22% in the observational phase (p<0.001). Median duration of counselling was 50 min. During the intervention phase, 78% received a phone follow-up for a median total duration of 42 min in 4 sessions. Prescription of nicotine replacement therapy at discharge increased from 18% to 58% in the intervention phase (risk ratio (RR): 3.3 (95% CI 2.4 to 4.3; p≤0.001). Smoking cessation at 12-month increased from 43% to 51% comparing the observation and intervention phases (RR=1.20, 95% CI 0.98 to 1.46; p=0.08; 97% with outcome assessment). In the control hospitals, the RR for quitting was 1.02 (95% CI 0.84 to 1.25; p=0.8, 92% with outcome assessment).Conclusions A proactive strategy offering intensive smoking cessation intervention based on MI to all smokers hospitalised for ACS significantly increases the uptake of smoking cessation counselling and might increase smoking abstinence at 12 months.