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Pharmacology and therapeutics
Research
Improvement of knowledge, attitude and perception of healthcare workers about ADR, a pre- and post-clinical pharmacists' interventional study
  1. Hossein Khalili1,
  2. Niayesh Mohebbi1,
  3. Narjes Hendoiee1,
  4. Abbas-Ali Keshtkar2,3,
  5. Simin Dashti-Khavidaki1
  1. 1Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  2. 2Endocrinology and Metabolism Research Center, Tehran University of Medical Sciences, Tehran, Iran
  3. 3Gasterology and Hepatology Research Center, Golestan University of Medical Sciences, Tehran, Iran
  1. Correspondence to Dr Hossein Khalili; khalilih{at}tums.ac.ir

Abstract

Purpose Healthcare workers have a main role in detection, assessment and spontaneous reporting of adverse drug reactions (ADRs), and improvement of their related knowledge, attitude and perception is essential. The goal of this study was evaluation of clinical pharmacists' interventions in improvement of knowledge, attitude and perception of healthcare workers about ADRs in a teaching referral hospital, Tehran, Iran.

Method Changes in knowledge, attitude and perception of healthcare workers of Imam teaching hospital about ADRs were evaluated before and after clinical pharmacists' interventions including workshops, meetings and presentations.

Results From the 100 participated subjects, 82 of them completed the study. 51% of the health workers have been aware of the Iranian Pharmacovigilance Center at the ministry of health before intervention and after that all the participants knew this centre. About awareness and detection of ADRs in patients, 69 (84.1%) healthcare workers recognised at least one, and following interventions, it was improved to 73 (89%). Only seven (8.5%) subjects have reported ADRs in before intervention phase that were increased significantly to 18 (22%) after intervention.

Conclusion Clinical pharmacists' interventions were successful in improvement of healthcare workers' knowledge, attitude and perception about ADRs and spontaneous reporting in our hospital.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/2.0/ and http://creativecommons.org/licenses/by-nc/2.0/legalcode.

https://doi-org.ezproxy.u-pec.fr/10.1136/bmjopen-2011-000367

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    Footnotes

    • To cite: Khalili H, Mohebbi N, Hendoiee N, et al. Improvement of knowledge, attitude and perception of healthcare workers about ADR, a pre- and post-clinical pharmacists' interventional study. BMJ Open 2012;2:e000367. doi:10.1136/bmjopen-2011-000367

    • Funding This study was supported by a grant from Office of Vice-Chancellor for Research of Tehran University of Medical Sciences.

    • Competing interests None.

    • Contributors HK and SD-K: clinical pharmacists of the hospital and provided educational programmes for the participants of the study and revised the manuscript. NM: data gathering and manuscript preparation. NH: data gathering and provided educational programme for the participants of the study. A-AK: study design and statistical analysis.

    • Provenance and peer review Not commissioned; externally peer reviewed.